Antimicrobial Activity of Some Complexes of Zr (IV) and Cd (II) with Benzaldazine Derivatives on Growth of Some Pathogenic Bacteria

مجلة التربية والعلم

Najwa Al-Barhawi¹  Zohour Daood²  Nahida Al-Chalabi³ 

[1] Department of Biology, College of Education for Pure Science, Mosul University, Mosul, Iraq;Dept. of Chemistry, College of Education for Pure Sciences, University of Mosul, Mosul, IRAQ;Dept. of Environment Sciences, College of Environmental Sciences and Technology, University of Mosul;

关键词: heavy metals;    pathogenic bacteria;    antibiotics;   

DOI  :  10.33899/edusj.2021.168655

来源: DOAJ

【 摘 要 】

In order to understand the medical effects of heavy metals, the antimicrobial effect of Cd (II) metal ion, Zr (IV) metal ion, Ligand and their complex compounds resulting from their combination, was studied on the growth of gram negative and positive bacteria as well as yeast. It turns out, that all bacterial isolates (Bacillus subtilus, Stapphylococcus aureus and Pseudomonas aeuroginosa, Escherichia coli, Klebsiella pneumonia, Proteus vulgaris, Salmonella typhi, Shigella flexneri and the yeast Candida albicans), have a high resistance of 100% to Colistin (10µg/disc) and Nystatin (10µg/disc), while the Zr (IV) metal is better than Cd metal in its effect on inhibiting the growth of different types of pathogenic bacteria isolated in this study.In the study of minimum inhibition concentration (MIC) of metal Cd (II), Zr (IV) and,  Ligand complexes, on the growth of bacterial isolates, it was also shown that Cd and Ligand 4-bromobenzaldazine (BrA) at the concentration 0.00025g/ml, had an effect of 88 and 100% as the lowest inhibitory concentration for the growth of all bacterial isolates of different species.

【 授权许可】

Unknown