High-resolution functional photoacoustic monitoring of vascular dynamics in human fingers

Photoacoustics

Chulhong Kim¹  Jin Young Kim²  Wonseok Choi²  Joongho Ahn² 

[1] Corresponding author.;Departments of Electrical Engineering, Convergence IT Engineering, Mechanical Engineering, and Medical Device Innovation Center, Pohang University of Science and Technology, Pohang, 37673, Republic of Korea;

关键词: Photoacoustic microscopy;    Blood vessel;    Hemodynamics;    Pulsation;    Perfusion;    Oxygen saturation;   

DOI  :  

来源: DOAJ

【 摘 要 】

Functional imaging of microvascular dynamics in extremities delivers intuitive information for early detection, diagnosis, and prognosis of vascular diseases. High-resolution and high-speed photoacoustic microscopy (PAM) visualizes and measures multiparametric information of microvessel networks in vivo such as morphology, flow, oxygen saturation, and metabolic rate. Here, we demonstrate high-resolution photoacoustic monitoring of vascular dynamics in human fingers. We photoacoustically monitored the position displacement of blood vessels associated with arterial pulsation in human fingers. Then, during and after arterial occlusion, we photoacoustically quantified oxygen consumption and blood perfusion in the fingertips. The results demonstrate that high-resolution functional PAM could be a vital tool in peripheral vascular examination for measuring heart rate, oxygen consumption, and/or blood perfusion.

【 授权许可】

Unknown