Anatomy and Imaging of Rat Prostate: Practical Monitoring in Experimental Cancer-Induced Protocols

Diagnostics

AnaI. Faustino-Rocha¹  Margarida Fardilha²  JoséM. Gonzalo-Orden³  Miguel Correia-Cardoso⁴  Mário Ginja⁴  Fernanda Seixas⁴  MariaJ. Pires⁴  PaulaA. Oliveira⁴  Rita Ferreira⁵ 

[1] Center for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), 5001-801 Vila Real, Portugal;Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal;Department of Medicine, Surgery and Veterinary Anatomy, University of León, 24071 León, Spain;Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro (UTAD), 5001-801 Vila Real, Portugal;Organic Chemistry, Natural Products and Food Stuffs (QOPNA), 3810-193 Aveiro, Portugal;

关键词: computed tomography (CT);    macroscopy;    magnetic resonance imaging (MRI);    microscopy;    ultrasonography;   

DOI  :  10.3390/diagnostics9030068

来源: DOAJ

【 摘 要 】

The rat has been frequently used as a model to study several human diseases, including cancer. In many research protocols using cancer models, researchers find it difficult to perform several of the most commonly used techniques and to compare their results. Although the protocols for the study of carcinogenesis are based on the macroscopic and microscopic anatomy of organs, few studies focus on the use of imaging. The use of imaging modalities to monitor the development of cancer avoids the need for intermediate sacrifice to assess the status of induced lesions, thus reducing the number of animals used in experiments. Our work intends to provide a complete and systematic overview of rat prostate anatomy and imaging, facilitating the monitoring of prostate cancer development through different imaging modalities, such as ultrasonography, computed tomography (CT) and magnetic resonance imaging (MRI).

【 授权许可】

Unknown