Sensitivity and specificity of magnetic resonance imaging in routine diagnosis of pulmonary lesions: a comparison with computed tomography

Journal of Thoracic Disease

article

Shuyi Yang¹  Fei Shan⁴  Yuxin Shi⁴  Tiefu Liu⁵  Qingle Wang¹  Haoling Zhang¹  Xingwei Zhang¹  Shan Yang¹  Zhiyong Zhang¹ 

[1] Department of Radiology, Zhongshan Hospital, Fudan University;Shanghai Institute of Medical Imaging;Department of Medical Imaging, Shanghai Medical College, Fudan University;Department of Radiology, Shanghai Public Health Clinical Center, Fudan University;Department of Scientific Research, Shanghai Public Health Clinical Center, Fudan University

关键词: Pulmonary nodule;    magnetic resonance imaging (MRI);    lung imaging reporting and data system (Lung-RADS);    computed tomography (CT);   

DOI  :  10.21037/jtd-22-370

学科分类：呼吸医学

来源: Pioneer Bioscience Publishing Company

【 摘 要 】

Background: State-of-the-art thoracic magnetic resonance imaging (MRI) plays a complementary role in the assessment of pulmonary nodules/masses which potentially indicate to cancer. We aimed to evaluate the sensitivity and specificity of MRI in diagnosis of pulmonary nodules/masses. Methods: Sixty-eight patients with computed tomography (CT)-detected pulmonary nodules/masses underwent 3T MRI (T1-VIBE, T1-starVIBE, T2-fBLADE turbo spin-echo, and T2-SPACE). The detection rate was calculated for each of the different subgroups of pulmonary nodules according to lung imaging reporting and data system (Lung-RADS). The four MRI sequences were compared in terms of detection rate and image quality-signal to noise ratio (SNR), contrast to noise ratio (CNR) and 5-point scoring scale. Agreement of lesion size measurement between CT and MRI was assessed by intraclass correlation coefficient (ICC). The picture-SNR, lesion-SNR and CNR of each sequence were analyzed by Mann-Whitney U test. Results: In total, 232 pulmonary lesions were detected by CT. The CT showed 86 solid nodules (SNs) 0.96. The picture-SNR, lesion-SNR and CNR by T1-starVIBE were higher than those by T1-VIBE (P<0.001). The lesion-SNR and CNR by T2-fBLADE TSE were higher than those by T2-SPACE (P=0.006, 0.038). 86% of images by T1-starVIBE, 92% by T2-fBLADE TSE, 90% by T2-SPACE and 93% by T1-VIBE were scored 3 or more. Conclusions: MRI achieves high sensitivity and specificity for different type of pulmonary nodules detection and is an effective alternative to CT as a diagnostic tool for pulmonary nodules.

【 授权许可】

Unknown