期刊论文详细信息
International Journal of Molecular Sciences
Voltammetric Behavior of o-Nitrophenol and Damage to DNA
关键词: o-Nitrophenol;    DNA-modified GCE;    DNA damage;    Electrochemical reduction;   
DOI  :  
来源: DOAJ
【 摘 要 】

The electrochemical behavior of o-nitrophenol was studied in detail with a glassy carbon electrode (GCE). The dependence of peak potential on pH indicated that equivalent electrons and protons were involved in the process of o-nitrophenol reduction. The interaction of o-nitrophenol with calf thymus DNA was investigated by adding DNA to the o-nitrophenol solution and by immobilizing DNA on GCE, respectively. The peak current decrement and peak potential shift in presence of DNA indicated that o-nitrophenol could interact with DNA. The result was demonstrated that the in situ DNA damage was detected by differential pulse voltammetry after the o-nitrophenol was electrochemically reduced.

【 授权许可】

Unknown   

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