Screening of ligands for the Ullmann synthesis of electron-rich diaryl ethers

Beilstein Journal of Organic Chemistry

Nicola Otto¹  Till Opatz¹ 

[1] Institute of Organic Chemistry, University of Mainz, Duesbergweg 10–14, 55128 Mainz, Germany;

关键词: catalysis;    C–O bond formation;    diaryl ethers;    nucleophilic aromatic substitution;    Ullmann-type coupling;   

DOI  :  10.3762/bjoc.8.122

来源: DOAJ

【 摘 要 】

In the search for new ligands for the Ullmann diaryl ether synthesis, permitting the coupling of electron-rich aryl bromides at relatively low temperatures, 56 structurally diverse multidentate ligands were screened in a model system that uses copper iodide in acetonitrile with potassium phosphate as the base. The ligands differed largely in their performance, but no privileged structural class could be identified.

【 授权许可】

Unknown