期刊论文详细信息
Molecules | |
Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues | |
Andreas Lanver1  | |
[1] id="af1-molecules-10-01169">Institut für Organische Chemie, Universität zu Köln, Greinstrasse 4, 50939 Köln, Germany Fax: (49)221-470-306 | |
关键词: Microwave; nucleophilic aromatic substitution; nucleosides; | |
DOI : 10.3390/10020508 | |
来源: mdpi | |
【 摘 要 】
An efficient protocol for the amination of 6-chloropurine derivatives through nucleophilic aromatic substitution under microwave irradiation was developed and applied to the synthesis in two steps of a series of new acyclic nucleosides (acyclovir analogues) starting from commercially available compounds.
【 授权许可】
Unknown
© 2005 by MDPI (http://www.mdpi.org).
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202003190060202ZK.pdf | 165KB | download |