Emerging Issues in Infective Endocarditis

Emerging Infectious Diseases

关键词: endocarditis;    diagnosis;    PCR;    16S rRNA;    historical;    fungi;   

DOI  :  10.3201/eid1006.030848

来源: DOAJ

【 摘 要 】

Infective endocarditis, a serious infection of the endocardium of the heart, particularly the heart valves, is associated with a high degree of illness and death. It generally occurs in patients with altered and abnormal heart architecture, in combination with exposure to bacteria through trauma and other potentially high-risk activities involving transient bacteremia. Knowledge about the origins of endocarditis stems from the work of Fernel in the early 1500s, and yet this infection still presents physicians with major diagnostic and management dilemmas. Endocarditis is caused by a variety of bacteria and fungi, as well as emerging infectious agents, including Tropheryma whipelli, Bartonella spp., and Rickettsia spp. We review the evolution of endocarditis and compare its progression with discoveries in microbiology, science, and medicine.

【 授权许可】

Unknown