The associations of psychological symptoms and cognitive patterns with pain and pain sensitization in people with hand osteoarthritis

Osteoarthritis and Cartilage Open

Tuhina Neogi¹  Pernille Steen Pettersen²  Knut Engedal²  Karin Magnusson³  Tore K. Kvien⁴  Torfinn L. Gaarden⁴  Elisabeth Mulrooney⁴  Hilde Berner Hammer⁵  Ida K. Haugen⁶  Hanne Dagfinrud⁷ 

[1] Corresponding author. Division of Rheumatology and Research, Diakonhjemmet Hospital, PB 23 Vinderen, 0370, Oslo, Norway.;Faculty of Medicine, University of Oslo, Oslo, Norway;Department of Geriatric Psychiatry, Diakonhjemmet, Oslo, Norway;Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway;National Advisory Unit on Rehabilitation in Rheumatology, Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway;Norwegian Centre of Ageing and Health, Vestfold County Hospital, Tønsberg and Oslo University Hospital, Ullevaal, Oslo, Norway;Section of Rheumatology, Boston University School of Medicine, Boston, United States;

关键词: Hand osteoarthritis;    Pain;    Pain sensitization;    Psychological factors;   

DOI  :  

来源: DOAJ

【 摘 要 】

Objective: To examine whether psychological symptoms and cognitive patterns are associated with self-reported pain and pain sensitization in people with hand osteoarthritis (OA). Design: In the Nor-Hand study (n ​= ​300), people with hand OA self-reported psychological symptoms (Hospital Anxiety and Depression Scale), cognitive patterns (Pain catastrophizing Scale and Arthritis Self-Efficacy Scale) as well as their pain severity in hands, overall pain and multi-joint pain. Central pain sensitization was measured clinically by temporal summation and pressure pain threshold tests. We examined whether psychological symptoms and cognitive patterns were cross-sectionally associated with pain using linear regression. Beta coefficients (β) per one standard deviation of the independent variable were presented. Stratified analyses were performed in cases of significant interactions (p ​< ​0.10). Results: Higher levels of anxiety, depressive symptoms and pain catastrophizing and low levels of self-efficacy were statistically significantly associated with higher levels of hand pain by Numeric Rating Scale (β ​= ​0.43, 0.48 and −0.57, respectively). Similar associations were found for overall pain, but not for measures of central pain sensitization. In stratified analyses, anxiety and depressive symptoms were more strongly related with pain in subgroups with younger age and higher comorbidity burden. Pain catastrophizing was more strongly related with pain in subgroups with younger age, overweight/obesity, higher comorbidity burden and poor sleep. Conclusion: Psychological symptoms and cognitive patterns were associated with self-reported OA pain, especially in people with younger age, overweight/obesity, higher comorbidity burden and poor sleep. No associations were found for psychological symptoms and cognitive patterns with pain sensitization.

【 授权许可】

Unknown