Oregano Essential Oil Micro- and Nanoencapsulation With Bioactive Properties for Biotechnological and Biomedical Applications

Frontiers in Bioengineering and Biotechnology

Juan Pérez Cano¹  Susana Esteban-Rubio¹  María Rosa Aguilar³  Blanca Vázquez-Lasa³  Gloria María Pontes-Quero³ 

[1] Alodia Farmacéutica SL, Santiago Grisolía 2 D130/L145, Madrid, Spain;Group of Biomaterials, Department of Polymeric Nanomaterials and Biomaterials, Institute of Polymer Science and Technology, ICTP-CSIC, Madrid, Spain;Networking Biomedical Research Centre in Bioengineering, Biomaterials and Nanomedicine, CIBER-BBN, Madrid, Spain;

关键词: microcarriers;    nanocarriers;    antimicrobial;    antibacterial;    antifungal;    emulsion;   

DOI  :  10.3389/fbioe.2021.703684

来源: DOAJ

【 摘 要 】

Due to the preservative, antioxidant, antimicrobial, and therapeutic properties of oregano essential oil (OEO), it has received an emerging interest for biotechnological and biomedical applications. However, stability and bioactivity can be compromised by its natural volatile and hydrophobic nature, and by external factors including light, heat, or oxygen. Therefore, micro- and nanoencapsulation are being employed to guarantee oregano oil protection from outside aggressions and to maximize its potential. Oregano oil encapsulation is an interesting strategy used to increase its stability, enhance its bioactivity, and decrease its volatility. At the same time, the versatility that micro- and nanocarriers offer, allows to prepare tailored systems that can provide a controlled and targeted release of the encapsulated principle, influence its bioactive activities, or even provide additional properties. Most common materials used to prepare these carriers are based on lipids and cyclodextrins, due to their hydrophobic nature, polymers due to their versatility in composition, and hybrid lipid-polymer systems. In this context, recently developed micro- and nanocarriers encapsulating oregano oil with applications in the biotechnological and biomedical fields will be discussed.

【 授权许可】

Unknown