Microbiota of Cow’s Milk with Udder Pathologies

Microorganisms

Vitaliy I. Mikhalev¹  Nikolay T. Klimov¹  Vitaliy I. Zimnikov¹  Evgeniy V. Mikhaylov¹  Yulia D. Dvoretskaya²  Vasily N. Popov²  Mariya V. Gryaznova²  Sergey A. Solodskikh²  Mikhail Y. Syromyatnikov² 

[1] FSBSI All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy, 394061 Voronezh, Russia;Laboratory of Metagenomics and Food Biotechnology, Voronezh State University of Engineering Technologies, 394036 Voronezh, Russia;

关键词: microbiome;    udder pathologies;    sequencing;    mastitis;    16S rRNA;   

DOI  :  10.3390/microorganisms9091974

来源: DOAJ

【 摘 要 】

Mastitis is the most common disease for cattle, causing great economic losses for the global dairy industry. Recent studies indicate the multi-agent and microbiome diversity of this disease. To understand the nature of mastitis and investigate the role of the microbiome in the development of pathologies in the udder of bovines, we performed NGS sequencing of the 16S rRNA gene of cow’s milk with pathologies of the udder. The obtained data show a significant increase in the Cutibacterium, Blautia, Clostridium sensu stricto 2, Staphylococcus, Streptococcus and Microbacterium genera for groups of cows with udder pathologies. Increasing relative abundance of the Staphylococcus and Streptococcus genera was associated with subclinical mastitis. Our data show that a relative increase in abundance of the Staphylococcus and Microbacterium genera may be an early sign of infection. We have shown, for the first time, an increase in the Colidextribacter, Paeniclostridium and Turicibacter genera in groups of cows with mastitis. These results expand our understanding of the role of the microbiome in the development of bovine mastitis.

【 授权许可】

Unknown