Early lessons from schistosomiasis mass drug administration programs [version 1; referees: 3 approved]

F1000Research

W. Evan Secor¹ 

[1] Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, 30329, USA;

关键词: Antimicrobials & Drug Resistance;    Community Ecology & Biodiversity;    Drug Discovery & Design;    Global Health;    Marine & Freshwater Ecology;    Medical Microbiology;    Parasitology;    Pediatric Infectious Diseases;    Population Ecology;    Tropical & Travel-Associated Diseases;   

DOI  :  10.12688/f1000research.6826.1

来源: DOAJ

【 摘 要 】

Mass drug administration using praziquantel is the backbone of the current strategy for the control of schistosomiasis. As the theoretical plans have moved into practical application, certain challenges with this approach have surfaced, and it is likely that annual mass drug administration alone may not be sufficient to achieve program goals. However, mass drug administration is still the only available intervention that can be readily used in the wide variety of settings where schistosomiasis is endemic. The task then becomes how to improve this approach and identify what adjuncts to mass drug administration are effective, as programs move from morbidity control to elimination goals. Other aspects worthy of consideration include how best to employ new diagnostic tools to more easily identify where treatment is needed, and new formulations of praziquantel to extend the availability of treatment to all age groups. The aim of this review is to highlight both areas of challenge and of opportunity to improve the public health impact of schistosomiasis control programs.

【 授权许可】

Unknown