The mobilization of free fatty acids in relation to adipose tissue triglyceride fatty acids in the rat

Journal of Lipid Research

J.D. Hunter¹  E.R. Nye¹  Hilaire Buchanan¹ 

[1] Department of Medicine, University of Otago Medical School, Dunedin, New Zealand;

关键词: gas-liquid chromatography;    lipolysis;    noradrenaline;    linseed oil;    coconut oil;    diet;   

DOI  :  

来源: DOAJ

【 摘 要 】

Three diets, consisting respectively of formulations high in oleic and stearic acid, linolenic acid, and lauric acid, were fed to rats until the adipose tissue TGFA largely reflected the dietary pattern of fatty acids. The composition of the serum FFA under basal conditions and following noradrenaline-stimulated lipolysis, were examined in relation to the respective adipose tissue TGFA. It was found in both in vivo and in vitro studies that lauric acid appeared to be less easily mobilized than longer chain acids. The in vitro studies indicated that this could not be explained either by positional preference of the shorter chain acids for the α-position of esterification or by increased reesterification of the shorter chain acids. The possibility remains that the difference is due to some specificity of tissue lipases for certain ester linkages.

【 授权许可】

Unknown