Virus-Incorporated Biomimetic Nanocomposites for Tissue Regeneration

Nanomaterials

MoonSung Kang¹  Su-Jin Song¹  Dong-Wook Han¹  YongCheol Shin²  Jin-Woo Oh²  Suong-Hyu Hyon³  Chuntae Kim⁴  IruthayapandiSelestin Raja⁵ 

[1] Nanotechnology, Pusan National University, Busan 46241, Korea;;Department of Cogno-Mechatronics Engineering, College of Nanoscience &Department of Medical Engineering, Yonsei University, College of Medicine, Seoul 03722, Korea;;Department of Nanofusion Technology, College of Nanoscience &Monocrystalline Bank Research Institute, Pusan National University, Busan 46241, Korea;

关键词: virus;    tissue regeneration;    biomimetic nanocomposites;    phage display;   

DOI  :  10.3390/nano9071014

来源: DOAJ

【 摘 要 】

Owing to the astonishing properties of non-harmful viruses, tissue regeneration using virus-based biomimetic materials has been an emerging trend recently. The selective peptide expression and enrichment of the desired peptide on the surface, monodispersion, self-assembly, and ease of genetic and chemical modification properties have allowed viruses to take a long stride in biomedical applications. Researchers have published many reviews so far describing unusual properties of virus-based nanoparticles, phage display, modification, and possible biomedical applications, including biosensors, bioimaging, tissue regeneration, and drug delivery, however the integration of the virus into different biomaterials for the application of tissue regeneration is not yet discussed in detail. This review will focus on various morphologies of virus-incorporated biomimetic nanocomposites in tissue regeneration and highlight the progress, challenges, and future directions in this area.

【 授权许可】

Unknown