Research Progress of M13 Bacteriophage-Based Biosensors

Nanomaterials

Jin-Woo Oh¹  EunJung Choi²  Dong-Wook Han³  Na-Na Jeong⁴  Jong-Ryeul Sohn⁴  Jong-Sik Moon⁵ 

[1] Nanotechnology, Pusan National University, Busan 46241, Korea;Department of BIT Fusion Technology Center, Pusan National University, Busan 46241, Korea;;Department of Cogno-Mechatronics Engineering, College of Nanoscience &Department of Public Health Sciences, Graduate School, Korea University, Seoul 02708, Korea;National Core Research Center for Hybrid Materials Solution, Pusan National University, Busan 46241, Korea;

关键词: virus;    biosensor;    m13 bacteriophage;    color sensor;    phage display;   

DOI  :  10.3390/nano9101448

来源: DOAJ

【 摘 要 】

Recently, new virus-based sensor systems that operate on M13 bacteriophage infrastructure have attracted considerable attention. These systems can detect a range of chemicals with excellent sensitivity and selectivity. Filaments consistent with M13 bacteriophages can be ordered by highly established forms of self-assembly. This allows M13 bacteriophages to build a homogeneous distribution and infiltrate the network structure of nanostructures under mild conditions. Phage display, involving the genetic engineering of M13 bacteriophages, is another strong feature of the M13 bacteriophage as a functional building block. The numerous genetic modification possibilities of M13 bacteriophages are clearly the key features, and far more applications are envisaged. This paper reviews the recent progress in the application of the M13 bacteriophage self-assembly structures through to sensor systems and discusses future M13 bacteriophage technology.

【 授权许可】

Unknown