Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease

Autopsy and Case Reports

Kirti Gupta¹  Suvradeep Mitra²  Vikarn Vishwajeet²  Arpitha Kollabathula²  Vibhav Sharma³  Ashish Bhalla³  Pallab Ray⁴ 

[1] Institute of Medical Education and Research - Department of Histopathology;Institute of Medical Education and Research, Department of Histopathology;Institute of Medical Education and Research, Department of Internal Medicine;Institute of Medical Education and Research, Department of Medical Microbiology;

关键词: Brucellosis;    Amyloidosis;    Autopsy;    Polycystic Kidney;    Autosomal Dominant;   

DOI  :  10.4322/acr.2019.128

来源: DOAJ

【 摘 要 】

We describe an autopsy case of a 45-year-old male diagnosed with autosomal dominant polycystic kidney disease who presented with complaints of altered sensorium. The autopsy revealed multiple tumor-like masses in the liver, which on histological examination depicted multiple large suppurative granulomas with the presence of variable acid-fast coccobacilli (consistent with Brucella spp.). Interestingly, extensive amyloid deposition in multiple organs was noted. To the best of our knowledge, this is the first case of chronic brucellosis causing tumor-like abscesses in the liver accompanied by secondary systemic amyloidosis in a patient with underlying autosomal dominant polycystic kidney disease.

【 授权许可】

Unknown