Cardiac amyloidosis: a challenging diagnosis

Autopsy and Case Reports

Graziele Cristina Palancio Morais¹  José Carlos de Aguiar Bonadia¹  Marjorie Moreira Arruda¹  Geanete Pozzan¹ 

[1] Department of Pathological Sciences – Faculdade de Ciências Médicas – Santa Casa de Misericórdia de São Paulo - São Paulo/SP;

关键词: Amyloidosis;    Cardiomyopathy;    Restrictive;    Autopsy;   

DOI  :  10.4322/acr.%y.98461

来源: DOAJ

【 摘 要 】

Cardiovascular involvement of amyloidosis is present in 90% of cases, which is frequently associated with the primary form of the disease (AL amyloidosis). Clinical manifestations are represented by heart failure due to restrictive myocardiopathy and electrical impulse conduction abnormalities, which are clinically remarkable in up to 50% of the cases. The prognosis of patients with systemic amyloidosis is directly associated with the presence of cardiac involvement, such that survival does not usually exceed 4 months after the onset of heart failure signs and symptoms. The authors report a case of primary systemic amyloidosis, diagnosed only at autopsy, with severe cardiac involvement.

【 授权许可】

Unknown