Integrating Microtissues in Nanofiber Scaffolds for Regenerative Nanomedicine

Materials

Manuel Arruebo¹  Nadia Benkirane-Jessel²  Sandy Eap²  Laetitia Keller²  Pascale Schwinté²  Damien Offner²  Quentin Wagner²  Jens M. Kelm³  Anne-Marie Musset⁴ 

[1] Department of Chemical Engineering and Aragon Nanoscience Institute, University of Zaragoza, C/Mariano Esquillor, s/n, Zaragoza 50018, Spain;INSERM (French National Institute of Health and Medical Research), “Osteoarticular and Dental Regenerative Nanomedicine” laboratory, UMR 1109, Faculté de Médecine, Strasbourg Cedex F-67085, France;InSphero AG, Wagistrasse 27, Schlieren 8952, Switzerland;Université de Strasbourg, Faculté de Chirurgie Dentaire, 1 place de l’Hôpital, Strasbourg F-67000, France;

关键词: nanofibrous implant;    microtissues;    regenerative nanomedicine;    bone regeneration;   

DOI  :  10.3390/ma8105342

来源: DOAJ

【 摘 要 】

A new generation of biomaterials focus on smart materials incorporating cells. Here, we describe a novel generation of synthetic nanofibrous implant functionalized with living microtissues for regenerative nanomedicine. The strategy designed here enhances the effectiveness of therapeutic implants compared to current approaches used in the clinic today based on single cells added to the implant.

【 授权许可】

Unknown