Metal-free synthesis of indolo[2,3-b]indoles through aerobic cascade dehydrogenative aromatization/oxidative annulation

Green Synthesis and Catalysis

Huawen Huang¹  Guo-Jun Deng²  Shanping Chen²  Pingyu Jiang²  Yi Xia²  Kai Hu² 

[1] Corresponding author.;Key Laboratory for Green Organic Synthesis and Application of Hunan Province, Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan 411105, China;

关键词: Dehydroaromatization;    Oxidative annulation;    Cascade reaction;    Indole;    Indole-fused compounds;   

DOI  :  

来源: DOAJ

【 摘 要 】

A convenient method for the rapid construction of indolo[2,3-b]indoles has been developed. This cascade reaction involving condensation, dehydroaromatization, and oxidative annulation was achieved in a one-pot TMSI/DMSO system, providing a diversity of functionalized indolo[2,3-b]indoles in satisfactory yields under facile metal-free conditions. The present protocol provides a straightforward approach to access structurally valuable indolo[2,3-b], indoles.

【 授权许可】

Unknown