Efficacy and Blood Plasmalogen Changes by Oral Administration of Plasmalogen in Patients with Mild Alzheimer's Disease and Mild Cognitive Impairment: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial

EBioMedicine

Chikako Wakana¹  Yoshio Tsuboi²  Tatsuo Yamada³  Shiro Mawatari⁴  Takehiko Fujino⁴  Takashi Asada⁵  Suminori Kono⁶ 

[1] BOOCS Clinic, 6-18 Tenya-machi, Hakata-ku, Fukuoka 812-0025, Japan;Department of Neurology, School of Medicine, Fukuoka University, 7-45-1 Nanakuma, Johnan-ku, Fukuoka 814-0180, Japan;Gotanda Rehabilitation Hospital, 8-8-20 Nishigotanda, Shinagawa-ku, Tokyo 141-0031, Japan;Institute of Rheological Functions of Food, 2241-1 Kubara, Hisayama-machi, Kasuya-gun, Fukuoka 811-2501, Japan;Memory Clinic Ochanomizu, 1-5-34, Yushima, Bunkyo-ku, Tokyo 113-0034, Japan;National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8636, Japan;

关键词: Plasmalogen;    Scallop;    Alzheimer's disease;    Mild cognitive impairment;    Cognitive function;   

DOI  :  10.1016/j.ebiom.2017.02.012

来源: DOAJ

【 授权许可】

Unknown