Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative review

Food Science and Human Wellness

Maria Eleonora Bizzoca¹  Lorenzo Lo Muzio¹  Vito Carlo Alberto Caponio¹  Eleonora Lo Muzio²  Stefania Leuci³  Michele Davide Mignogna³ 

[1] Department of Clinical and Experimental Medicine, University of Foggia, Foggia 71122, Italy;Department of Neuroscience and Rehabilitation, University of Ferrara, Ferrara 44121, Italy;Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples 80131, Italy;

关键词: Natural compounds;    SARS-CoV-2;    COVID-19;    Prevention;    Infectious disease;    Phytochemicals;   

DOI  :  

来源: DOAJ

【 摘 要 】

Coronavirus pandemic infection is the most important health issue worldwide. Coronavirus disease 2019 is a contagious disease characterized by severe acute respiratory syndrome coronavirus 2. To date, excluding the possibility of vaccination, against SARS-CoV-2 infection it is possible to act only with supportive care and non-virus-specific treatments in order to improve the patient's symptoms. Pharmaceutical industry is investigating effects of medicinal plants, phytochemical extracts and aromatic herbs to find out natural substances which may act as antiviral drugs. Several studies have revealed how these substances may interfere with the viral life cycle, viral entry, replication, assembly or discharge, as well as virus-specific host targets or stimulating the host immune system, reducing oxidative stress and inflammatory response. A natural compound can be used as a prophylaxis by people professionally exposed to the risk of contagion and/or positive patients not in intensive care. The aim of this paper is to perform a narrative review of current literature in order to summarize the most studied natural compounds and their modes of action.

【 授权许可】

Unknown