Effects of probiotics fermented milk products on obesity measure among adults: A systematic review and meta-analysis of clinical trials

Journal of Functional Foods

Maryam Miraghajani¹  Zahra Faghihimani²  Hamed Mohammadi³  Rahele Ziaei⁴  Abed Ghavami⁵  Shima Sharifi⁵  Elyas Nattagh-Eshtivani⁶ 

[1] Corresponding authors at: Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, PO Box 81745, Isfahan, Iran. (R Ziaei). Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. The Early Life Research Unit, Academic Division of Child Health, Obstetrics and Gynaecology, and Nottingham Digestive Disease Centre and Biomedical Research Centre, The School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK (Maryam Miraghajani).;Department of Clinical Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran;Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran;Department of Community Nutrition, School of Nutrition and Food Sciences, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran;Student Research Committee, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran;Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran;

关键词: Meta-analysis;    Obesity;    Overweight;    Probiotics fermented milk;    Gut microbiota;   

DOI  :  

来源: DOAJ

【 摘 要 】

Current evidence suggests that gut dysbiosis has a pivotal role in progression of obesity. Probiotics fermented milk products (PFMP) by influencing the functions of gut microbiota might bring protective effects against obesity; however, findings of available randomized controlled trials (RCTs) are conflicting. The aim of this study was systematically review and analyse RCTs assessing the effects of PFMP supplementation on anthropometric indices. PubMed, Scopus, ISI Web of science and Cochrane Library were searched up to August 2020. A total of 19 RCTs (with 22 treatment arms) were included and reporting data about PFMP and body weight (BW), body mass index (BMI), waist circumference (WC) and body fat percentage (BF%) were analyzed. Two authors independently extracted the data and assessed the risk of bias using the Cochran risk of bias tool PFMP intervention indicated a significant reduction in BW and BMI. Although this reduction in WC and BF% were non-significant. PFMP provide new opportunities to manage obesity.

【 授权许可】

Unknown