Impact of lung block shape on cardiac dose for total body irradiation

Physics and Imaging in Radiation Oncology

Minsun Kim¹  Kent Wallner²  Samuel M.H. Luk³  Yolanda D. Tseng³  Mallory C. Glenn³  Ralph Ermoian³  Mark Phillips³ 

[1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States;Corresponding author at: Department of Radiation Oncology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, United States.;Department of Radiation Oncology, University of Washington, Seattle, WA, United States;

关键词: Radiation;    Oncology;    Total;    Body;    Heart;    Blocks;   

DOI  :  

来源: DOAJ

【 摘 要 】

Evaluating cardiac dose during total body irradiation (TBI) is of increasing interest. A three-dimensional beam model for TBI was commissioned and lung shielding was simulated in a treatment planning system with the cardiac silhouette partially blocked and unblocked. When blocked, the median heart dose decreased by 6% (IQR = 6%) and the median cardiac V12Gy decreased by 27% (IQR = 17%). The median left anterior descending artery dose decreased 20% (IQR = 12%) for blocked cases. Because using partial heart shielding may result in considerable changes in dose to cardiac structures, TBI protocols should explicitly consider lung block design parameters and their potential effects.

【 授权许可】

Unknown