Chemical and biological properties of puffed Dendrobium officinale extracts: Evaluation of antioxidant and anti-fatigue activities

Journal of Functional Foods

Kyungae Jo¹  Kwang-Won Yu²  Ki-Bae Hong³  Hyung Joo Suh³  Singeun Kim³  Sung Hee Han⁴  Bum Sun Byun⁵ 

[1] BK21 Plus, College of Health Science, Korea University, Seoul 02841, Republic of Korea;Department of Food and Nutrition, Korea National University of Transportation, Jeungpyeong 27909, Republic of Korea;Department of Integrated Biomedical and Life Sciences, Graduate School, Korea University, Seoul 02841, Republic of Korea;Research Affairs, College of Medicine, Korea University Anam Hospital, Seoul 02841, Republic of Korea;Yuequan Fengzhiling Health Technology Co., LTD., Building No 3, Heshengguomao Center, Xihu District, Hangzhou City, Zhejiang Province 310000, China;

关键词: Dendrobium officinale;    Antioxidant activity;    Anti-fatigue;    Explosive puffing;    Forced swimming test;   

DOI  :  

来源: DOAJ

【 摘 要 】

Dendrobium officinale (D. officinale, DO) is a traditional medicinal herb used in China. Phytochemicals and its antioxidant activity of puffed dendrobium extract was measured for antioxidant capacity. Physiological mechanism on skeletal muscle was analyzed by blood glucose, lactic acid, glycogen and ATP content and mRNA gene expression. Antioxidant effect of the extract on liver were measured. The extraction yield and phytochemical contents in DO extract were increased by the change of puffing pressure. In addition, antioxidant activities creased after explosive puffing process. DO extract treated with explosive puffing at high dose was significantly prolonged in swimming time. The glycogen content of puffing DO at high dose was significantly different. The expression of the PGC1-α and the level of ATP in PHD was higher. Explosive puffing DO strongly improve fatigue resistance of mice correlated with inhibiting the depletion of glycogen stores, regulating oxidation related enzymes, and modulating the activation of PGC-1α.

【 授权许可】

Unknown