Biomedical Application of Functional Materials in Organ-on-a-Chip

Frontiers in Bioengineering and Biotechnology

Xianghua Yan¹  Xiang Chen³  Qinshu Kang³  Chizhu Ding³ 

[1] Hubei Provincial Engineering Laboratory for Pig Precision Feeding and Feed Safety Technology, Wuhan, China;State Key Laboratory of Agricultural Microbiology, College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan, China;State Key Laboratory of Agricultural Microbiology, College of Science, Huazhong Agricultural University, Wuhan, China;The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China;

关键词: organ-on-a-chip;    microfluidics;    elastomer;    hydrogel;    microfabrication;   

DOI  :  10.3389/fbioe.2020.00823

来源: DOAJ

【 摘 要 】

The organ-on-a-chip (OOC) technology has been utilized in a lot of biomedical fields such as fundamental physiological and pharmacological researches. Various materials have been introduced in OOC and can be broadly classified into inorganic, organic, and hybrid materials. Although PDMS continues to be the preferred material for laboratory research, materials for OOC are constantly evolving and progressing, and have promoted the development of OOC. This mini review provides a summary of the various type of materials for OOC systems, focusing on the progress of materials and related fabrication technologies within the last 5 years. The advantages and drawbacks of these materials in particular applications are discussed. In addition, future perspectives and challenges are also discussed.

【 授权许可】

Unknown