AGREEing on clinical practice guidelines for idiopathic steroid-sensitive nephrotic syndrome in children

Systematic Reviews

on behalf of the Saudi Society of Nephrology and Transplantation¹  Turki Al Hussain²  Weiam Almaiman²  Abdulhadi Al Talhi³  Majed Aloufi⁴  Rolan K. Bassrawi⁵  Reem Al Khalifah⁶  Mohamad-Hani Temsah⁷  Jameela A. Kari⁸  Khalid Abdulaziz Alhasan⁹  Abdullah Al Salloum⁹  Rupesh Raina^1,10  Sidharth Kumar Sethi^1,11  Muddathir Hamad^1,12  Adi Alherbish^1,13  Yasser Sami Amer^1,14  Muneera AlJelaify^1,15  Naif Abdulmajeed^1,16  Reny Joseph^1,17 

[1] ;College of Medicine, Alfaisal University;Department of Pediatric Nephrology, Pediatrics Hospital, King Saud Medical City;Department of Pediatric Nephrology, Prince Sultan Military Medical City;General Pediatrics Unit, Pediatrics Department, King Khalid University Hospital, King Saud University Medical City;Pediatric Endocrinology Unit, Pediatrics Department, College of Medicine, King Saud University;Pediatric Intensive Care Unit, Pediatric Department, College of Medicine, King Saud University;Pediatric Nephrology Division, Department of Pediatrics, Pediatric Nephrology Center of Excellence Faculty of Medicine, King Abdulaziz University;Pediatric Nephrology Unit, Pediatrics Department, College of Medicine, King Saud University;Pediatric Nephrology, Akron Children’s Hospital;Pediatric Nephrology, Medanta, The Medicity;Pediatric Neurology Unit, Pediatrics Department, King Khalid University Hospital, King Saud University Medical City;Pediatrics Department, College of Medicine, King Saud University;Pediatrics Department, King Khalid University Hospital;Pharmacy Services Department, King Khalid University Hospital, King Saud University Medical City;Prince Sultan Military Medical City;Ward 11B and Day Care, Pediatrics-Nursing, King Khalid University Hospital, King Saud University Medical City;

关键词: Nephrotic syndrome;    Pediatrics;    Clinical practice guidelines;    Systematic review;    AGREE II Instrument;    Quality assessment;   

DOI  :  10.1186/s13643-021-01666-w

来源: DOAJ

【 摘 要 】

Abstract Background Nephrotic syndrome is the most common kidney disease in children worldwide. Our aim was to critically appraise the quality of recent Clinical Practice Guidelines (CPGs) for idiopathic steroid-sensitive nephrotic syndrome (SSNS) in children in addition to summarize and compare their recommendations. Methods Systematic review of CPGs. We identified clinical questions and eligibility criteria and searched and screened for CPGs using bibliographic and CPG databases. Each included CPG was assessed by four independent appraisers using the Appraisal of Guidelines for REsearch & Evaluation II (AGREE-II) instrument. We summarized the recommendations in a comparison practical table. Results Our search retrieved 282 citations, of which three CPGs were eligible and appraised: Kidney Disease: Improving Global Outcomes (KDIGO) 2012, Japan Society for Pediatric Nephrology (JSPN) 2014, and American Academy of Pediatrics (AAP) 2009. Among these, the overall assessment of two evidence-based CPGs scored > 70% (KDIGO and JSPN), which was consistent with their higher scores in the six domains of the AGREE II Instrument. In domain 3 (rigor of development), KDIGO, JSPN, and AAP scored 84%, 74%, and 41%, respectively. In domain 5 (applicability), they scored 22%, 16%, and 19%, respectively, and in domain 6 (editorial independence), they scored 94%, 65%, and 88%, respectively. Conclusions The methodological quality of the KDIGO CPG was superior, followed by JSPN and AAP CPGs with the relevant recommendations for use in practice. Systematic review registration The protocol was registered in the Center for Open Science (OSF) DOI: 10.17605/OSF.IO/6QTMD and in the International prospective register of systematic reviews PROSPERO 2020 CRD42020197511 .

【 授权许可】

Unknown