Integrating neuroimaging and gene expression data using the imaging transcriptomics toolbox

STAR Protocols

Ottavia Dipasquale¹  Daniel Martins²  Federico Turkheimer²  Steven C.R. Williams³  Matteo Frigo⁴  Alessio Giacomel⁴  Mattia Veronese⁴ 

[1] ATHENA Project Team, Inria Sophia Antipolis - Mediterranée, Université Côte d’Azur, Nice, France;Corresponding author;Corsmed AB, Stockholm, Sweden;Department of Neuroimaging, IoPPN, King’s College London, London, UK;

关键词: Bioinformatics;    Sequence analysis;    Health Sciences;    Neuroscience;    Computer sciences;   

DOI  :  

来源: DOAJ

【 摘 要 】

Summary: The integration of neuroimaging and transcriptomics data, Imaging Transcriptomics, is becoming increasingly popular but standardized workflows for its implementation are still lacking. We describe the Imaging Transcriptomics toolbox, a new package that implements a full imaging transcriptomics pipeline using a user-friendly, command line interface. This toolbox allows the user to identify patterns of gene expression which correlates with a specific neuroimaging phenotype and perform gene set enrichment analyses to inform the biological interpretation of the findings using up-to-date methods.For complete details on the use and execution of this protocol, please refer to Martins et al. (2021).

【 授权许可】

Unknown