Effectiveness of an Active and Continuous Surveillance Program for Intensive Care Units Infections Based on the EPIC III (Extended Prevalence of Infection in Intensive Care) Approach

Journal of Clinical Medicine

Titty Vita Vignola¹  Rosario Urbino²  Martina Scanu²  Stefano Bosso³  Giulia Catozzi⁴  Silvia Corcione⁵  Francesco Giuseppe De Rosa⁵  Giorgia Montrucchio⁶  Gabriele Sales⁶  Andrea Costamagna⁶  Luca Brazzi⁶  Claudia Filippini⁶ 

[1] Anesthesia and Intensive Care Unit, San Giovanni Bosco Hospital, 10154 Turin, Italy;Department of Anaesthesia, Critical Care and Emergency, Città Della Salute e Della Scienza Hospital, Corso Dogliotti 14, 10126 Turin, Italy;Department of Anesthesiology and Critical Care, “Cardinal Massaia” Hospital, 14100 Asti, Italy;Department of Health Sciences, University of Milan, 20122 Milan, Italy;Department of Medical Sciences, Infectious Diseases, University of Turin, 10126 Turin, Italy;Department of Surgical Sciences, University of Turin, 10126 Turin, Italy;

关键词: infections;    intensive care unit;    antimicrobial stewardship;    infection control;    drug resistance;    bacterial;   

DOI  :  10.3390/jcm11092482

来源: DOAJ

【 摘 要 】

We evaluated the effectiveness of the Extended Prevalence of Infection in Intensive Care (EPIC) III data collection protocol as an active surveillance tool in the eight Intensive Care Units (ICUs) of the Intensive and Critical Care Department of the University Hospital of Turin. A total of 435 patients were included in a six-day study over 72 ICU beds. 42% had at least one infection: 69% at one site, 26% at two sites and 5% at three or more sites. ICU-acquired infections were the most common (64%), followed by hospital-associated infections (22%) and community-acquired (20%), considering that each patient may have developed more than one infection type. 72% of patients were receiving at least one antibiotic: 48% for prophylaxis and 52% for treatment. Mortality, the length of ICU and hospital stays were 13%, 14 and 29 days, respectively, being all estimated to be significantly different in patients without and with infection (8% vs. 20%; 4 vs. 20 and 11 vs. 50 (p < 0.001). Our data confirm a high prevalence of infections, sepsis and the use of antimicrobials. The repeated punctual prevalence survey seems an effective method to carry out the surveillance of infections and the use of antimicrobials in the ICU. The use of the European Centre for Disease Prevention and Control (ECDC) definitions and the EPIC III protocol seems strategic to allow comparisons with national and international contexts.

【 授权许可】

Unknown