The Antimicrobial Stewardship Approach to Combating Clostridium Difficile

Antibiotics

Eric Wenzler¹  Surafel G. Mulugeta¹  Larry H. Danziger¹ 

[1] College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA; E-Mails:

关键词: antimicrobial stewardship;    Clostridium difficile;    restriction;    diarrhea;    rapid diagnostics;    treatment;    infection control;   

DOI  :  10.3390/antibiotics4020198

来源: mdpi

【 摘 要 】

Clostridium difficile remains a major public health threat and continues to contribute to excess morbidity, mortality and healthcare costs. Antimicrobial stewardship programs have demonstrated success in combating C. difficile, primarily through antibiotic restrictive strategies. As the incidence and prevalence of C. difficile associate disease continues to increase both in the hospital and community setting, additional stewardship approaches are needed. This manuscript reviews stewardship interventions that have been successful against C. difficile associated disease and proposes future tactics that antimicrobial stewardship programs may employ to develop a more global approach to combat this difficult pathogen.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.