Expanding Genetic Code Expansion through Resource Facilities, Workshops, and Conferences

International Journal of Molecular Sciences

RyanA. Mehl¹  E.James Petersson²  ChristopherA. Ahern³ 

[1] Department of Biochemistry and Biophysics, Oregon State University, 2011 Ag Life Sciences Building, Corvallis, OR 97331, USA;Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104-6323, USA;Department of Molecular Physiology and Biophysics, The University of Iowa, 4270 Carver Biomedical Research Building, 285 Newton Road, Iowa City, IA 52242, USA;

关键词: genetic code expansion;    unnatural amino acid;    non-canonical amino acid;    amber suppression;   

DOI  :  10.3390/ijms20092103

来源: DOAJ

【 摘 要 】

Genetic Code Expansion (GCE) enables the encoding of amino acids with diverse chemical properties. This approach has tremendous potential to advance biological discoveries in basic research, medical, and industrial settings. Given the multiple technical approaches and the associated research activities used to achieve GCE, herein we have taken the opportunity to describe ongoing out-reach efforts in the GCE community. These include Resource Facilities that nucleate expertise and reagents within a specific GCE discipline, hands-on Workshops to provide GCE training, and GCE Conferences which bring the community together in a collegial setting. The overall goal of these activities is to accelerate the integration of GCE approaches into more research settings and to facilitate solutions to common technical hurdles.

【 授权许可】

Unknown