Synthesis of monodisperse spherical AgNPs by ultrasound-intensified Lee-Meisel method, and quick evaluation via machine learning

Ultrasonics Sonochemistry

Guohao Mu¹  Zonghua Xiao²  Zhixiang Wang³  Hongliang Qian³  Dechun Huang³  Mengjun Wang³  Bin Dong³  Lin Dai³  Wei Chen³  Ning Xue⁴ 

[1] Health Sciences, University of Nottingham, Nottingham NG7 2UH, United Kingdom;Department of Food Quality and Safety/National R&D Center for Chinese Herbal Medicine Processing, School of Engineering, China Pharmaceutical University, Nanjing, 211198, China;Department of Pharmaceutical Engineering, School of Engineering, China Pharmaceutical University, Nanjing, 211198, China;;Faculty of Medicine &

关键词: AgNPs;    Sonocrystallization;    Ultrasound-intensified digestive ripening;    Lee-Meisel method;   

DOI  :  

来源: DOAJ

【 摘 要 】

Due to the high reactivity of Ag+ and uncontrolled growth process, the AgNPs produced by conventional Lee-Meisel method always exhibited larger particle size (30–200 nm) and polydisperse morphology (including spherical, triangular, and rod-like shape). An ultrasound-intensified Lee-Meisel (UILM) method is developed in this study to environmental-friendly and controllable synthesize monodisperse spherical AgNPs (~3.7 nm). Effects of Ag:citrate ratio (1:3 or 5:4), ultrasound power (300 to 1200 W) and reaction time (4 to 24 min) on the physical–chemical properties of AgNPs are investigated systematically. The transmission electron microscope (TEM) images, UV–Vis spectra, average particle size, zeta potential and pH value all demonstrate that crystallization and digestive ripening processes are facilitated in the presence of ultrasound irradiation. Therefore, both chemical reaction rate and mass transfer rate are enhanced to accelerate primary nucleation and inhibit uncontrolled particle growth, leading to the formation of monodisperse spherical AgNPs. Moreover, a machine learning approach - Decision Tree Regressor in conjunction with Shapley value analysis reveal the concentration of reactants is a more important feature affecting the particle.

【 授权许可】

Unknown