Young-onset type 2 diabetes in South Korea: a review of the current status and unmet need

The Korean Journal of Internal Medicine

Kyungdo Han¹  Nam Hoon Kim²  Ye Seul Yang³  Tae Seo Sohn³ 

[1] Department of Statistics and Actuarial Science, Soongsil University, Seoul, Korea;Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea;Division of Endocrinology and Metabolism, Department of Internal Medicine, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea;

关键词: diabetes mellitus, type 2;    young adult;    diabetes complications;    epidemiology;    treatment adherence and compliance;   

DOI  :  10.3904/kjim.2021.379

来源: DOAJ

【 摘 要 】

The prevalence of young-onset (diagnosis at age < 40 years) type 2 diabetes mellitus (T2DM) is increasing globally. Young-onset T2DM has a common pathophysiology of glucose dysregulation as in late-onset T2DM. However, it presents a greater association with obesity and a more rapid decline in β-cell function than late-onset T2DM. Accumulating evidence indicates that disease progression in young-onset T2DM is rapid, resulting in early and frequent development of microvascular and macrovascular complications, as well as premature death. Improper management and low adherence to medical therapy are important issues in young-onset T2DM. This review discusses the epidemiology, disease entity, and clinical issues associated with young-onset T2DM. We also present the prevalence and clinical characteristics of patients with young-onset T2DM in South Korea.

【 授权许可】

Unknown