Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole Derivatives

Molecules

关键词: Conducting materials;    supramolecular synthons;    pyrroles;   

DOI  :  10.3390/80700536

来源: DOAJ

【 摘 要 】

We present 1-pentafluorophenyl-1H-pyrrole and some of its electrophilic substitution reactions: formylation and acetylations. The 2-substituted products formed in these reactions are selectively and in high yield converted into 3-substituted products by treatment with trifluoromethanesulfonic acid. A general synthesis of 3-acylpyrroles was developed by the trifluoromethanesulfonic acid-mediated rearrangement of the corresponding 2-acylpyrroles.

【 授权许可】

Unknown