Synthesis and Reactivity of New 1-Pentafluorophenyl-1H-pyrrole Derivatives

Molecules

Katarína Hrnლriková¹ 

[1] id="af1-molecules-08-00536">Department of Organic Chemistry, Slovak University of Technology, Radlinského Street 9, SK-812 37 Tel. [phone], Fax. [phone]

关键词: Conducting materials;    supramolecular synthons;    pyrroles;   

DOI  :  10.3390/80700536

来源: mdpi

【 摘 要 】

We present 1-pentafluorophenyl-1H-pyrrole and some of its electrophilic substitution reactions: formylation and acetylations. The 2-substituted products formed in these reactions are selectively and in high yield converted into 3-substituted products by treatment with trifluoromethanesulfonic acid. A general synthesis of 3‑acylpyrroles was developed by the trifluoromethanesulfonic acid–mediated rearrangement of the corresponding 2-acylpyrroles.

【 授权许可】

Unknown   
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