Living Materials for Regenerative Medicine

Engineered Regeneration

Qiao Wang¹  Yunru Yu²  Chong Wang²  Luoran Shang² 

[1] Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang 325000, China;Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, and the Shanghai Key Laboratory of Medical Epigenetics, the International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Institutes of Biomedical Sciences, Fudan University, Shanghai, China;

关键词: Regenerative medicine;    Living materials;    Tissue engineering;    Microfluidics;    Cell therapy;   

DOI  :  

来源: DOAJ

【 摘 要 】

Regenerative medicine has been attracting tremendous attention during the past few decades because it is promising in overcoming the limitations of donor shortage and immune complications in direct transplantations. The ongoing progress in this field calls for the rapid growth of living materials, which consist of live biological agents and can be designed together with synthetic materials to meet the application demands of regenerative medicine. In this review, we present a summary of the state-of-the-art progress of living materials that are applied in regenerative medicine. We first introduce the advanced engineering approaches that are employed to prepare living materials containing live cells, typically including genetic engineering, cell coating, microfluidics, and bioprinting, etc. Afterwards, we enumerate different application aspects of living materials in regenerative medicine, including tissue scaffold, cell therapy, tissue models, and so on. Finally, we give a concise conclusion and provide a perspective of this field.

【 授权许可】

Unknown