Natural and Synthetic Coumarins with Effects on Inflammation

Molecules

Ahmed Bakr Abdelwahab¹  Gilbert Kirsch¹  Patrick Chaimbault¹ 

[1] SRSMC, UMR 7565, Groupe HeCRIN, ICPM, 1 boulevard Arago, 57070 Metz, France;

关键词: coumarins;    furocoumarins;    pyranocoumarins;    inflammation;   

DOI  :  10.3390/molecules21101322

来源: DOAJ

【 摘 要 】

In this review, we will present the different aspects of coumarins and derivatives, from natural origins or synthetically prepared, and their action on inflammation. Coumarins and also furo- and pyranocoumarins are found in many different plants. These compounds are very often investigated for antioxidant properties. Other biological properties are also possible and anti-inflammation activity is one of these. As coumarins are also available quite easily via synthesis, natural ones can be prepared this way but derivatives with special substituents are also feasible. A review on the same topic appeared in 2004 and our contribution will take into account everything published since then.

【 授权许可】

Unknown