Associations amongst form of cocaine used (powder vs crack vs both) and HIV-related outcomes

Addictive Behaviors Reports

Nioud Mulugeta Gebru¹  Veronica L. Richards²  Emma C. Spencer³  Yiyang Liu³  Robert L. Cook⁴ 

[1] College of Medicine, University of Florida, 2004 Mowry Road, PO Box 100231, Gainesville 32610-0231, FL, USA.;;Corresponding author at: Department of Epidemiology, College of Public Health and Health Professions &Department of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, FL, USA;Department of Health Education and Behavior, College of Health and Human Performance, University of Florida, Gainesville, FL, USA;

关键词: Cocaine;    Crack;    HIV infection;    PWH;    Viral suppression;    Treatment adherence;   

DOI  :  

来源: DOAJ

【 摘 要 】

Introduction: Cocaine (including powder and crack) use is common among people with HIV (PWH). We identified socio-demographic and behavioral factors associated with cocaine use (overall and various forms) among PWH; we also examined differences in HIV treatment outcomes across cocaine exposure groups. Methods: The study sample (N = 1166) was derived from two cohorts of PWH in Florida between 2014 and 2020. Baseline data were linked to the Enhanced HIV/AIDS Reporting System (eHARS) which tracks HIV viral load. Socio-demographics and polysubstance use were compared by cocaine use and the three cocaine use groups (powder only n = 101, crack only n = 91, or both n = 65). The association between the three cocaine use groups, ART adherence, and HIV viral suppression (<200 copies/mL) in the following year was assessed by multivariate logistic regression. Results: People who used cocaine had lower HIV treatment adherence and viral suppression than those who did not use. People who used powder cocaine only were more likely to be younger, Hispanic/Latinx, and employed than those who used crack only or both. Compared to people who used both powder and crack cocaine, those who used one form of cocaine had 3 + odds of having durable viral suppression in the following year. Conclusion: The dual use of both powder and crack cocaine was associated with significantly worse HIV outcomes compared to use of only one form of cocaine. Screening for powder and crack cocaine use and timely intervention are needed to improve HIV treatment outcomes among this high-risk population.

【 授权许可】

Unknown