Differences of serum interleukin-6 levels in normotensive and preeclampsia women

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Lumbanraja, S.N.^1 ; Junitasari, R.^1 ; Pasaribu, H.P.^1

Fetomaternal Division, Departement of Obstetrics and Gynecology, Haji Adam Malik General Hospital, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia^1

关键词: Antiretrovirals;    Complete blood counts;    Cross-sectional study;    General hospitals;    HIV infection;    Inflammatory activity;    Interleukin-6;    Statistical significance;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012197/pdf
DOI  :  10.1088/1755-1315/125/1/012197

来源: IOP

【 摘 要 】

Red cell distribution width (RDW) has been shown higher with the increase of inflammatory activity. As CD4 count is not available in all cities in Indonesia, RDW was hoped to be the next promising marker to predict the progression of HIV infection. This study aims to find the association of RDW with aCD4 count in HIV-positive reproductive women in Indonesia. It was a prospective cross sectional study enrolled 37 consented outpatients HIV-positive reproductive women in Haji Adam Malik General Hospital, Medan, Indonesia. A 10 mL blood was taken, separated into two tubes for complete blood count and CD4 count. Data were collected and analyzed with SPSS 19.Mean CD4 absolute was lowest in >14.5% RDW group but without statistical significance. By classify CD4 absolute count, CD4 absolute ≤350/mm3showed significantly higher RDW than CD4 absolute >350/mm3(13.98±2.10% vs 12.79±0.88%; p=0.02). No correlation was between RDW and CD4 absolute, as well as, with CD4%.In conclusion, high RDW can be a promising marker to predict the low CD4 count in HIV-positive reproductive women within antiretroviral therapy.