Prevalence and predictors of non-alcoholic fatty liver disease in tertiary care hospital of Taif, Saudi Arabia: A retrospective study

Saudi Journal of Biological Sciences

Yasser A. Alharthi¹  Majid Alhomrani¹  Zaher M. Alghamdi¹  Walaa F. Alsanie²  Abdulhakeem S. Alamri³  Ahmad Joman Alghamdi³  Syed Mohammed Basheeruddin Asdaq³  Abdualmohsen A. Al-Subaie³  Hesham H. Alqurashi⁴ 

[1] Centre of Biomedical Sciences Research (CBSR), Deanship of Scientific Research, Taif University, Saudi Arabia;Corresponding author at: Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.;Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia;Department of Radiology, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia;

关键词: Nonalcoholic fatty liver disease;    Obesity;    Type 2 diabetes;    Risk factors;    Age;    Fasting blood glucose;   

DOI  :  

来源: DOAJ

【 摘 要 】

Background: The prevalence of nonalcoholic fatty liver disease (NAFLD) in Saudi Arabia is predicted to exceed 30% by 2030. NAFLD leads to liver fibrosis, thus increasing morbidity and health care burden. Obesity and diabetes have been strongly associated with NAFLD in different cities in Saudi Arabia. Objectives: Therefore, we aim to determine the prevalence rate of NAFLD and specific risk factors for NAFLD among patients of tertiary care hospital of Taif city. Material and methods: We retrospectively analyzed the medical records of patients for two years, between Feb 2017 and Feb 2019, (n = 100) referred to the hepatology clinic at King Abdulaziz Specialist Hospital in Taif. The diagnosis of NAFLD was based on the radiology report for patients who were aged >20 years old. Other parameters including fasting blood glucose (FBG), platelets count, alanine transaminase (ALT), aspartate transaminase (AST) and total bilirubin were statistically analyzed. Results: We found that 40% (P < 0.05) of all patients had NAFLD. The results revealed that a significantly high number of patients with NAFLD have high FBG levels (75%, P < 0.0001) and total bilirubin (P < 0.05). Meanwhile, platelet count was significantly reduced in patients with NAFLD (P < 0.05). Conclusion: NAFLD can be a serious health problem in the Taif region. In addition, high FBG is a significant specific risk factor for NAFLD. Health care providers should pay more attention to limiting the prevalence of NAFLD and its risk factors.

【 授权许可】

Unknown