Nano-Modified Titanium Implant Materials: A Way Toward Improved Antibacterial Properties

Frontiers in Bioengineering and Biotechnology

Chengliang Yang¹  Chong Wang²  Jinguang Yao³  Jia Liu³  Kegong Xie³  Maryam Tamaddon⁵  Yujin Tang⁵  Chaozong Liu⁶  Shokouh Attarilar⁶  Liqiang Wang⁷  Jianqiao Liu⁷ 

[1] Orthopaedic Science, University College London, The Royal National National Orthopaedic Hospital, Stanmore, United Kingdom;College of Mechanical Engineering, Dongguan University of Technology, Dongguan, China;Department of Orthopaedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China;Department of Pediatric Orthopaedics, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China;;Institute of Orthopaedic and Musculoskeletal Science, Division of Surgery &State Key Laboratory of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai, China;Youjiang Medical University for Nationalities, Baise, China;

关键词: bactericidal;    nanostructure;    antibacterial;    nanoparticles;    titanium-implants;   

DOI  :  10.3389/fbioe.2020.576969

来源: DOAJ

【 摘 要 】

Titanium and its alloys have superb biocompatibility, low elastic modulus, and favorable corrosion resistance. These exceptional properties lead to its wide use as a medical implant material. Titanium itself does not have antibacterial properties, so bacteria can gather and adhere to its surface resulting in infection issues. The infection is among the main reasons for implant failure in orthopedic surgeries. Nano-modification, as one of the good options, has the potential to induce different degrees of antibacterial effect on the surface of implant materials. At the same time, the nano-modification procedure and the produced nanostructures should not adversely affect the osteogenic activity, and it should simultaneously lead to favorable antibacterial properties on the surface of the implant. This article scrutinizes and deals with the surface nano-modification of titanium implant materials from three aspects: nanostructures formation procedures, nanomaterials loading, and nano-morphology. In this regard, the research progress on the antibacterial properties of various surface nano-modification of titanium implant materials and the related procedures are introduced, and the new trends will be discussed in order to improve the related materials and methods.

【 授权许可】

Unknown