Synthesis of copolymer eugenol crosslinked with divinyl benzene and preliminary study on its antibacterial activity

13th Joint Conference on Chemistry

Prasetya, Nor Basid Adiwibawa^1 ; Ngadiwiyana^1 ; Ismiyarto^1 ; Sarjono, P.R.^1

Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University, Semarang, Indonesia^1

关键词: Anti-bacterial activity;    antibacterial;    Divinyl benzenes;    divinylbenzene;    Eugenol;    Gram-negative bacteria;    Gram-positive bacterium;    Staphylococcus aureus;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/509/1/012102/pdf
DOI  :  10.1088/1757-899X/509/1/012102

来源: IOP

【 摘 要 】

Copolymer eugenol-divinyl benzene (PEDVB) was successfully synthesized via eugenol copolymerization with divinyl benzene using BF3 as a catalyst. The resulting copolymer was characterized using FTIR. Its antibacterial activity was tested using agar disc diffusion method by calculating the inhibitory zone diameters against Escherichia coli as a gram-negative bacteria and Staphylococcus aureus as a gram-positive bacterium. In addition, ampicillin and DMSO were used as a positive control and a negative control, respectively. The results showed that PEDVB performs antibacterial activity with slow response category.