期刊论文详细信息
Molecules
Epilobium angustifolium L. Extracts as Valuable Ingredients in Cosmetic and Dermatological Products
Edyta Makuch1  Paula Ossowicz-Rupniewska1  Łukasz Kucharski2  Wiktoria Duchnik2  Adam Klimowicz2  Anna Nowak2  Urszula Adamiak-Giera3  Piotr Prowans4  Norbert Czapla4  Jan Petriczko4  Marta Markowska4  Piotr Bargiel4  Martyna Zagórska-Dziok5 
[1] Department of Chemical Organic Technology and Polymeric Materials, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, PL-70322 Szczecin, Poland;Department of Cosmetic and Pharmaceutical Chemistry, Pomeranian Medical University in Szczecin, PL-70111 Szczecin, Poland;Department of Pharmacokinetics and Therapeutic Drug Monitoring, Pomeranian Medical University in Szczecin, PL-70111 Szczecin, Poland;Department of Plastic, Endocrine and General Surgery, Pomeranian Medical University in Szczecin, PL-72010 Police, Poland;Department of Technology of Cosmetic and Pharmaceutical Products, Medical College, University of Information Technology and Management in Rzeszow, Sucharskiego 2, PL-35225 Rzeszów, Poland;
关键词: fireweed;    antioxidants;    anti-inflammatory properties;    antiaging properties;    collagenase;    penetration skin;   
DOI  :  10.3390/molecules26113456
来源: DOAJ
【 摘 要 】

Epilobium angustifolium L. is a popular and well-known medicinal plant. In this study, an attempt to evaluate the possibility of using this plant in preparations for the care and treatment of skin diseases was made. The antioxidant, antiaging and anti-inflammatory properties of ethanolic extracts from Epilobium angustifolium (FEE) were assessed. Qualitative and quantitative evaluation of extracts chemically composition was performed by gas chromatography with mass spectrometry (GC-MS) and high-performance liquid chromatography (HPLC). The total polyphenol content (TPC) of biologically active compounds, such as the total content of polyphenols (TPC), flavonoids (TFC), and assimilation pigments, as well as selected phenolic acids, was assessed. FEE was evaluated for their anti-inflammatory and antiaging properties, achieving 68% inhibition of lipoxygenase activity, 60% of collagenase and 49% of elastase. FEE also showed high antioxidant activity, reaching to 87% of free radical scavenging using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 59% using 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS). Additionally, in vitro penetration studies were performed using two vehicles, i.e., a hydrogel and an emulsion containing FEE. These studies showed that the active ingredients contained in FEE penetrate through human skin and accumulate in it. The obtained results indicate that E. angustifolium may be an interesting plant material to be applied as a component of cosmetic and dermatological preparations with antiaging and anti-inflammatory properties.

【 授权许可】

Unknown   

  文献评价指标  
  下载次数:0次 浏览次数:0次