The niche of One Health approaches in Lassa fever surveillance and control

Annals of Clinical Microbiology and Antimicrobials

Liã Bárbara Arruda¹  Margaret J. Thomason¹  Elisabeth Fichet-Calvet²  Danny Asogun³  Deborah Ehichioya³  Ayodeji Olayemi⁴  Adesola Yinka-Ogunleye⁵  Chikwe Ihekweazu⁵  Rashid Ansumana⁶  David Simons⁷  Najmul Haider⁷  Richard A. Kock⁷ 

[1] Centre for Clinical Microbiology, Division of Infection and Immunity, University College London;Department of Virology, Bernhard Nocht Institute for Tropical Medicine;Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital;Natural History Museum, Obafemi Awolowo University;Nigeria Centre for Disease Control;School of Community Health Sciences, Njala University;The Royal Veterinary College, University of London;

关键词: Lassa fever;    One Health;    Zoonosis;    Emerging infectious diseases;   

DOI  :  10.1186/s12941-021-00431-0

来源: DOAJ

【 摘 要 】

Abstract Lassa fever (LF), a zoonotic illness, represents a public health burden in West African countries where the Lassa virus (LASV) circulates among rodents. Human exposure hinges significantly on LASV ecology, which is in turn shaped by various parameters such as weather seasonality and even virus and rodent-host genetics. Furthermore, human behaviour, despite playing a key role in the zoonotic nature of the disease, critically affects either the spread or control of human-to-human transmission. Previous estimations on LF burden date from the 80s and it is unclear how the population expansion and the improvement on diagnostics and surveillance methods have affected such predictions. Although recent data have contributed to the awareness of epidemics, the real impact of LF in West African communities will only be possible with the intensification of interdisciplinary efforts in research and public health approaches. This review discusses the causes and consequences of LF from a One Health perspective, and how the application of this concept can improve the surveillance and control of this disease in West Africa.

【 授权许可】

Unknown