Experimental use of fibrin glue derived from snake venom in non-pregnant canine uterus

Journal of Venomous Animals and Toxins including Tropical Diseases

关键词: healing;    fibrin glue;    uterus;    surgical adhesives;    wound closure;   

DOI  :  10.1590/S1678-91992004000200003

来源: DOAJ

【 摘 要 】

This study evaluated the use of fibrin glue derived from snake venom in the healing process after canine hysterorrhaphy. Three groups of four animals were submitted to uterine hysterotomy followed by wound closure. In Group 1, double-layer suture was used, the first with Schimieden pattern, the second with Cushing pattern; in Group 2, only fibrin glue; and in Group 3, the same as for Group 1 but with fibrin glue as suture reinforcement. Results indicated that fibrin glue produced less inflammation in the exudative phase, and exacerbated deposition of connective tissue and angiogenesis in the proliferative and maturation phases of the healing process, favoring its evolution.

【 授权许可】

Unknown