The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity

Molecules

关键词: Mizoroki–Heck reaction;    palladium;    1,2-dienes;    1,3-dienes;   

DOI  :  10.3390/molecules15042667

来源: DOAJ

【 摘 要 】

This review is an overview of the last ten years’ use of the Mizoroki–Heck coupling applied to 1,2- and 1,3-dienes. Since both these systems form π-allyl palladium intermediates in Pd(0) coupling, they show particular chemical behavior. Many examples of 1,2-dienes Heck reactions are presented. 1,2-Dienes are important substrates because of their high reactivity that makes them useful building blocks for the synthesis of biologically relevant structures.

【 授权许可】

Unknown