Modern Synthetic Methods for the Stereoselective Construction of 1,3-Dienes

Molecules

RaquelG. Soengas¹  Humberto Rodríguez-Solla¹ 

[1] Department of Organic and Inorganic Chemistry, University of Oviedo, Julián Clavería 6, 33006 Oviedo, Spain;

关键词: 1,3-dienes;    dienylation;    cross-coupling;    olefin metathesis;   

DOI  :  10.3390/molecules26020249

来源: DOAJ

【 摘 要 】

The 1,3-butadiene motif is widely found in many natural products and drug candidates with relevant biological activities. Moreover, dienes are important targets for synthetic chemists, due to their ability to give access to a wide range of functional group transformations, including a broad range of C-C bond-forming processes. Therefore, the stereoselective preparation of dienes have attracted much attention over the past decades, and the search for new synthetic protocols continues unabated. The aim of this review is to give an overview of the diverse methodologies that have emerged in the last decade, with a focus on the synthetic processes that meet the requirements of efficiency and sustainability of modern organic chemistry.

【 授权许可】

Unknown