Molecules | |
The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity | |
Annamaria Deagostino1  Cristina Prandi1  Silvia Tabasso1  | |
[1] Dipartimento di Chimica Generale e Chimica Organica, Università di Torino, Via Pietro Giuria, 7, I 10125, Torino, Italy | |
关键词: Mizoroki–Heck reaction; palladium; 1; 2-dienes; 1; 3-dienes; | |
DOI : 10.3390/molecules15042667 | |
来源: mdpi | |
【 摘 要 】
This review is an overview of the last ten years’ use of the Mizoroki–Heck coupling applied to 1,2- and 1,3-dienes. Since both these systems form π-allyl palladium intermediates in Pd(0) coupling, they show particular chemical behavior. Many examples of 1,2-dienes Heck reactions are presented. 1,2-Dienes are important substrates because of their high reactivity that makes them useful building blocks for the synthesis of biologically relevant structures.
【 授权许可】
CC BY
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
【 预 览 】
Files | Size | Format | View |
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RO202003190054248ZK.pdf | 378KB | download |