Thirtieth Anniversary of the Discovery of Laxaphycins. Intriguing Peptides Keeping a Part of Their Mystery

Marine Drugs

Isabelle Bonnard¹  Laurine Darcel¹  Sanjit Das¹  Bernard Banaigs¹  Nicolas Inguimbert¹ 

[1] CRIOBE, USR EPHE-UPVD-CNRS 3278, Université de Perpignan Via Domitia, 58 Avenue Paul Alduy, 66860 Perpignan, France;

关键词: laxaphycin;    cyanobacteria;    synthesis;    biosynthesis;    marine natural product;    peptide;   

DOI  :  10.3390/md19090473

来源: DOAJ

【 摘 要 】

Lipopeptides are a class of compounds generally produced by microorganisms through hybrid biosynthetic pathways involving non-ribosomal peptide synthase and a polyketyl synthase. Cyanobacterial-produced laxaphycins are examples of this family of compounds that have expanded over the past three decades. These compounds benefit from technological advances helping in their synthesis and characterization, as well as in deciphering their biosynthesis. The present article attempts to summarize most of the articles that have been published on laxaphycins. The current knowledge on the ecological role of these complex sets of compounds will also be examined.

【 授权许可】

Unknown