Venetoclax in association with decitabine as effective bridge to transplant in a case of relapsed early T‐cell lymphoblastic leukemia

Clinical Case Reports

Bianca Mecacci¹  Marzia Defina¹  Sara Ciofini¹  Monica Bocchia¹  Elisabetta Zappone¹  Donatella Raspadori¹  Anna Sicuranza¹  Emanuele Cencini¹  Alessandro Gozzetti¹ 

[1] Hematology Unit Azienda Ospedaliera Universitaria Senese University of Siena Siena Italy;

关键词: acute lymphoblastic leukemia;    allogeneic transplantation;    decitabine;    relapse;    venetoclax;   

DOI  :  10.1002/ccr3.3041

来源: DOAJ

【 摘 要 】

Abstract A case of an early‐relapsed high‐risk T‐ALL with high BCL‐2 expression on leukemic blasts was successfully treated with decitabine and venetoclax, achieving a CR. We suggest decitabine and venetoclax should be synergistic in BCL2‐positive ALL.

【 授权许可】

Unknown