Technology for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva IPC-Think Tank (Part 2)

Antimicrobial Resistance and Infection Control

the 2017 Geneva IPC-Think Tank¹  Eli Perencevich²  Carolyn Tarrant³  Andreas Widmer⁴  Benedetta Allegranzi⁵  Claire Kilpatrick⁵  Julie Storr⁵  Sara Tomczyk⁵  Didier Pittet⁶  Walter Zingg⁶  Karl-Heinz Krause⁷  Raheelah Ahmad⁸  Enrique Castro-Sanchez⁸  Denise Cardo⁹  Benjamin J. Park⁹ 

[1]

[2]Carver College of Medicine, University of Iowa

[3]Department of Health Sciences, University of Leicester

[4]Infection Control Programme, University Hospitals of Basel

[5]Infection Prevention and Control Global Unit, World Health Organization

[6]Infection control programme and WHO collaborating center, University of Geneva Hospitals and Faculty of Medicine

[7]Institute of Genetics and Genomics, University of Geneva

[8]National Institute for Health Research in Healthcare Associated Infection and Antimicrobial Resistance, Imperial College London

[9]US Centers for Disease Control and Prevention

关键词: Technology;    Infection prevention and control;    Microbiome;    Whole genome sequencing;    Copper;    Hand hygiene;   

DOI  :  10.1186/s13756-019-0538-y

来源: DOAJ

【 摘 要 】

Abstract Background The high burden of healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) is partially due to excessive antimicrobial use both in human and animal medicine worldwide. How can technology help to overcome challenges in infection prevention and control (IPC) and to prevent HAI and emerging AMR? Methods In June 2017, 42 international experts convened in Geneva, Switzerland to discuss four potential domains of technology in IPC and AMR: 1) role and potential contribution of microbiome research; 2) whole genome sequencing; 3) effectiveness and benefit of antimicrobial environmental surfaces; and 4) future research in hand hygiene. Results Research on the microbiome could expand understanding of antimicrobial use and also the role of probiotics or even faecal transplantation for therapeutic purposes. Whole genome sequencing will provide new insights in modes of transmission of infectious diseases. Although it is a powerful tool for public health epidemiology, some challenges with interpretation and costs still need to be addressed. The effectiveness and cost-effectiveness of antimicrobially coated or treated environmental high-touch surfaces requires further research before they can be recommended for routine use. Hand hygiene implementation can be advanced, where technological enhancement of surveillance, technique and compliance are coupled with reminders for healthcare professionals. Conclusions The four domains of technological innovation contribute to the prevention of HAI and AMR at different levels. Microbiome research may offer innovative concepts for future prevention, whole genome sequencing could detect new modes of transmission and become an additional tool for effective public health epidemiology, antimicrobial surfaces might help to decrease the environment as source of transmission but continue to raise more questions than answers, and technological innovation may have a role in improving surveillance approaches and supporting best practice in hand hygiene.

【 授权许可】

Unknown